Thursday, 29 January 2015

In the Way Cancer Cells Work Together, a Possible Tool for Their Demise

A tumor, as strange as it may sound, is a little society. The cancer cells that make it up cooperate with one another, and together they thrive.

Scientists are only starting to decipher the rules of these communities. But if they can understand how these cells work together, then they may be able to stop the tumor. “You can drive it to collapse,” said Marco Archetti, a biologist at the University of East Anglia and at the Icahn School of Medicine at Mount Sinai.

Cancer starts when healthy cells mutate and lose the safeguards that normally keep their growth in check. The cells start to multiply quickly, and their descendants gain new mutations, some of which make the cells even better at multiplying.
As tumors rapidly develop, they outgrow their blood supply, and stores of nutrients and growth-stimulating chemicals, known as growth factors, run low. As it turns out, cancer cells survive this harsh new environment by helping one another.

New mutations can cause cancer cells to start making their own growth factors, and they don’t keep these essential chemicals to themselves. Growth factors seep throughout the tumor, affecting all the cells. “It’s one of the hallmarks of cancer,” Dr. Archetti said.

This kind of cellular cooperation can get complicated, as Dr. Edward J. Gunther, an oncologist at Penn State College of Medicine, and his colleagues discovered while studying breast cancer tumors in mice. More


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Friday, 23 January 2015

See 3 Moons of Jupiter Perform Rare Triple Transit Friday Night

On Friday night (Jan. 23), observers all across North America will witness a rare event when three of Jupiter's moons, and their shadows, pass across the face of the giant planet.

How rare are these Jupiter triple transits? I have seen two in the last 15 years personally, but the next one will not occur until 2032.

As Galileo found early in the 17th century, Jupiter has four large, bright moons that are usually seen as points of light on one side of the planet or the other. These satellites — Io, Europa, Ganymede and Callisto — are known as the Galilean moons, after their discoverer. Jupiter has at least 63 smaller moons, most of which are too small to be seen with amateur telescopes. [Photos: The Galilean Moons of Jupiter]

As the Galilean moons revolve around the giant planet, they sometimes pass in front of it and sometimes are lost in its shadow or behind the planet itself. In addition, all four moons cast their own shadows on Jupiter's cloud tops.


Because of the complex gravitational interaction between Jupiter and its moons, their motions are not independent, but are locked in specific patterns. The orbital periods of the three inner moons are as follows: Io, 1.769 days; Europa, 3.551 days; Ganymede, 7.155 days. More

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Sunday, 11 January 2015

TOSHIBA Encore Mini WT7-C-100 Tablet

Processor
type : Next gen Intel® Atom™ processor for tablets Z3735G with Intel® Burst Technology 2.0
clock speed : 1.33 (1.83 with Burst) GHz
2nd level cache : 2 MB
Operating System / Platform
Windows 8.1 with Bing

Design Colour
colour : Genchaku White 
Solid State Drive
capacity : 16 GB
System memory
standard : 1 GB (onboard)
technology : DDR3L RAM (1333 MHz) 
Display
size : 7.0” / 17.8cm
type : Multi Touch Wide Super VGA Display (WSVGA), 16:9 aspect ratio
internal resolution : 1,024 x 600 
Graphics adaptor
type : Intel® HD Graphics
memory type : shared 
Internal video modes
The following internal video modes are supported: :
resolution : 1,024 x 600 
Interfaces
1 × built-in microphone
1 × external Headphone (stereo) / Microphone combo socket
1 × micro-USB 2.0
1 × micro-SD™ card slot with SDHC™ / SDXC™ UHS-I support
1 × 2 MP rear camera
1 × 0.3 MP front camera
Wireless communication
Compliancy : Wi-Fi®
Network Support : 802.11b/g/n (up to 150 Mbps)
Wireless Technology : Wireless LAN
Wireless Technology : Bluetooth® 4.0 + LE 
Sound system
speakers : built-in speakers 
Keyboard
special features : Virtual keyboard (supports external keyboard via USB or Bluetooth) 
Pointing device
type : Virtual Mouse (supports external mouse via USB)
type : Capacitive touch display with 5 points multi-finger support 
Battery
technology : Lithium-ion polymer, 1 cell
maximum life : estimated sample figures:
6.5h 720p Video Playback 100% backlight : 60nits
5.2h 720p Video Playback 100% backlight : 200nits
7.3h User scenario: 65% Web, WLAN for WiFi model/10% Video Playback/25% Standby
32Weeks System Off
108h RTC Battery Life 
AC adaptor
input voltage : autosensing AC adapter (100/240 V) for worldwide usage
output voltage : 5 V
output current : 1.5 A
Physical dimensions
W x D x H : 199 x 119.8 x 10.9 mm
weight : starting at 0.350 kg
Warranty
1 year European Carry-in incl. local Pick-up & Return in the UK & Ireland. Toshiba also offers a large range of services to upgrade your standard warranty, please have a look at our website www.toshiba.co.uk/services to find the right service for your product. 
Bundled software
McAfee LiveSafe™ - Protects ALL your devices (complimentary 30 day subscription)
Office 365 Personal 1 year subscription included. Office activation required within 6 months of Windows activation date. Office 365 Personal provides the latest, full Microsoft Office applications, including Word, Excel, PowerPoint, OneNote and Outlook, for a tablet. Subscription includes 60 world minutes per month on Skype and 1TB base allowance on OneDrive (upgradeable).
TOSHIBA Display Utility 
Special features
3D Acceleration sensor 
Certification
The manufacturer declares that this product complies with the following directives and regulations for the CE-marking. Responsible for CE marking is Toshiba Europe GmbH, Hammfelddam 8, 41460 Neuss, Germany. 

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NADRA

NATIONAL DATABASE & REGISTRATION AUTHORITY

NADRA is one of the leading System Integrators in the global identification sector and boasts extensive experience in designing, implementing and operating solutions for corporate and public sector clients. NADRA offers its clients a portfolio of customizable solutions for identification, e-governance and secure documents. NADRA has successfully implemented the Multi-Biometric National Identity Card & Multi-Biometric e-Passport solutions for Pakistan, Passport Issuing System forKenya, Bangladesh High Security Driver’s License, and Civil Registration Management System for Sudan amongst other projects. National Database & Registration Authority (NADRA) has gained international recognition for its success in providing solutions for identification, e-governance and secure documents that deliver multi-pronged goals of mitigating identity theft, safe-guarding the interests of our clients, and facilitating the public. In-depth Research and Development efforts have enabled NADRA to become the trailblazer in the area of Software Integration, Data Warehousing, Network Infrastructure Development and Project Management.

MOBLINK GSM

MOBLINK GSM
Moblink is the largest cellular network in Pakistan and it has been providing mobile service since 1994. Mobilink is Pakistan’s leading provider of voice and data services, bringing more people together through service excellence and product innovation. With more than 36 million subscribers, Mobilink maintains market leadership through cutting-edge, integrated technology, the strongest brands and the largest portfolio of value added services in the industry, a broadband carrier division providing next generation internet technology as well as the country’s largest network with over 9,000 cell sites making everyday a better day for its customers.

PIA

PAKISTAN INTERNATIONAL AIRLINE
PIA is the official Airline and some other private airlines Airblue, Air Indus and Shaheen Air also working in Pakistan and PIA fleet include different aircraft like Airbus 310, Being 777, being 747 and being 737. On 11th of March, 1955, government of Pakistan founded Pakistan International Airline to merge Orient Airways and other airlines into PIA. Your comfort and convenience mean the world to us. Business Plus Lounges will serve you at all international and major domestic stations where you can sit back and relax. For the comfort of Business Class passengers at Karachi, Lahore, and Islamabad airports, PIA has its own exclusive Business Plus Lounges. Our hospitable staff will ensure that you're well looked after during your stay with us at the airport. PIA's Business Plus Lounges are equipped with the latest magazines and newspapers, Internet access, cable television, and snacks, so you can enjoy the best of Pakistani traditions in a modern, comfortable environment.

STATE BANK OF PAKISTAN

State Bank of Pakistan is official and central bank and head of all financial institutions in Pakistan and it established in 1948. Under the State Bank of Pakistan Order 1948, the Bank was charged with the duty to "regulate the issue of Bank notes and keeping of reserves with a view to securing monetary stability in Pakistan and generally to operate the currency and credit system of the country to its advantage". The scope of the Bank’s operations was considerably widened in the State Bank of Pakistan Act 1956, which required the Bank to regulate the monetary and credit system of Pakistan and to foster its growth in the best national interest with a view to securing monetary stability and fuller utilization of the country’s productive resources.

SUPARCO

PAKISTAN SPACE AND UPPER ATMOSPHERE RESEARCH COMMISSION

Pakistan Space and Upper Atmosphere Research Commission (SUPARCO), the national space agency, was established in 1961 as a Committee and was granted the status of a Commission in 1981. SUPARCO is mandated to conduct R&D in space science, space technology, and their peaceful applications in the country. It works towards developing indigenous capabilities in space technology and promoting space applications for socio-economic uplift of the country.

pakistan post

PAKISTAN POST OFFICE

Pakistan Post Office is one of the oldest government departments in the Sub-Continent. In 1947, it began functioning as the Department of Post & Telegraph. In 1962 it was separated from the Telegraph & Telephone and started working as an independent attached department. Pakistan Post is providing postal services in every nook and corner of the country through a network of around 13,000 post offices. Pakistan Post is providing delivery services to about 20 million households and businesses as community service without any cost considerations. In addition to its traditional role, the Pakistan Post also performs agency functions on behalf of Federal and Provincial governments, which inter-alias include Savings Bank, Postal Life Insurance, Collection of Taxes, Collection of Electricity, Water, Sui Gas and Telephone bills.

IMMIGRATION & PASSPORT

The Office of DG. (Immigration and Passport) is an attached department of Ministry of Interior, responsible to deal with the matters concerning issuance of Passports, Visas, Pakistan Citizenship and Renunciation of Pakistan Citizenship Certificates. This website will guide you about the processes for acquiring these documents.